XI International Conference on AIDS|
July 7-12, 1996
Ettiegne-Traore Virginie, Ghys P.D.*,
Coulibaly I-M., Laga M.
**CDC, Atlanta, GA, USA
HIV Seroincidence and STD Prevalence During an Intervention Study Among Female Sex Workers in Abidjan, Cote D'Ivoire: Preliminary Findings
ObjectivesTo compare the HIV seroincidence rate in female sex workers (FSW) before and during an intervention study, and to study the effect of two different STD diagnosis and treatment strategies on STD prevalence during this study.
MethodsA cross-sectional study (CS) of STD and HIV infection in FSW has been conducted at a confidential clinic in Abidjan since October 1992. In June 1994, an intervention study (IS) was started for FSW who were HIV-seronegative in the CS; HIV serology is repeated if the interval between the CS visit and enrollment in the IS is greater than two weeks. During the IS, women report once a month to the clinic where they receive health education, free condoms and free treatment for STD. FSW are randomized into those who are examined only when symptomatic and treated according to a basic STD diagnosis and treatment strategy (Group 1), and those who are examined systematically every month and treated according to an intensive STD diagnosis and treatment strategy (Group 2). An outcome assessment including serology for HIV, culture for N. gonorrhoeae (NG), EIA for C. trachomatis (CT) and wet mount for T. vaginalis (TV) is performed every six months.
ResultsBefore the IS, 5 HIV-1 seroconversions were observed during 24.six person-years (PY) in 39 FSW (20/100 PY). During the IS, 2 HIV-1 seroconversions have been observed during 30 PY in 44 FSW (7/100 PY) (RR 0.33; 95% CI 0.03 - 2.00). At the first IS outcome assessment, no significant differences were detected between Group 1 (N=21) and Group 2 (N=23) in mean number of visits (4.3 vs 4.1), in NG/CT prevalence (0% vs 5%), or in TV prevalence (19% vs 13%). Group 1 women, who had a less intensive diagnosis and treatment strategy, had a lower mean number of TV treatments (0.5 vs 0.8, p=NS) and NG/CT treatments (0.9 vs 2.3, p<.05).
ConclusionsThe HIV-1 seroincidence has decreased, although not significantly, during an intervention study among FSW in Abidjan. To date, no differences in STD prevalence have been observed between women who are treated according to the basic or the intensive STD diagnosis and treatment strategies. Further follow-up will enable us to determine the optimal strategy for STD diagnosis and treatment to control HIV and STD in FSW in Abidjan.
|XI Int. Conference on AIDS abstracts...||
Created: July 16, 1996|
Last modified: July 17, 1996
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